With inherent benefits including its speed time to results and application flexibility, the convenience and effectiveness of MALDI-TOF MS is magnified by virtue of its low sample volume requirements and broad sample content salts, buffers amenability. Dramatic increases in the depth of MALDI analyses have been made routine by intuitive software, and easy automation allows for high throughput solutions.
The matrix is ionized with a laser beam, and transfers the charge to the analytes, generating singly charged ions from analytes in the sample that are then accelerated. Since the discovery of MALDI in the mid 80's this fast and high-throughput enabling ionization made its way into a variety of applications.
The laser aiming at different positions gives rise to spatial, molecular information as used e. The smarter way to protein characterization, glycoprotein analysis, QC applications, polymer analysis, ultra-high throughput screening and MS Imaging. Ideally suited to perform top-down, middle-down, and bottom-up sequencing approaches, as well as glycoprotein analysis, for efficient biopharmaceutical research.
Rapid answers to your QC or synthesis control questions. The quality needed for high resolution imaging while keeping your instrument cleaner for longer. MALDI consumables. Your effortless time-to-result has never been faster. Proven AnchorChip technology for easiest automation, as well as standard formats available with 96, or spot geometry.
These data are also used to classify tissue — so called tissue typing. Polymer Manufacturing. Depending on the biokemiska tester eller maldi-tof depth needed microflex® LRF or autoflex® maX series in combination with BioPharma Compass® software are perfect solutions.
Molecular changes originate at the cellular level and solution-based techniques can lack sensitivity to capture changes produced from small cell populations, whereas MALDI can work directly of tissue. Untargeted Biomarker Discovery. Also, higher level protein structure can be examined via the detection and localization of di- and trisulfide bonds.
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Mass Spectrometry. Bruker LabScape maintenance agreements offer solutions to fit and match individual customer requirements to ensure the highest standards of reliability and productivity. For Research Use Only.